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Akt activity protects rheumatoid synovial fibroblasts from Fas-induced apoptosis by inhibition of Bid cleavage

The morphological responses can be assessed by light and electron microscopy and immunohistochemistry and should be interpreted in conjunction with clinical pathology alterations (Ennulat et al

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If we are to achieve this ambitious objective, we will first need to identify valuable biological markers and to develop imaging techniques of better predictive value