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Helps prevent darkening of the skin

According to the results of the most recent meta-analysis, including data from more than 4 million patients, the global incidence of statin intolerance is 9.1%, and if intolerance is diagnosed using existing definitions, including the ILEP definition [153], the incidence ranges from 5.9% to 7% [411]

Consistent with this, loss of the trisulfide bond sharply reduced SQORs thermal denaturation temperature from 66 C to 36.5 C (Figure 2 shows the crystal structure of human SQOR

This antioxidative effect is also observed with caffeine and paraxanthine [10], which are known to upregulate endogenous antioxidant systems [43], thereby protecting neurons from oxidative damage [44]

Proc Natl Acad Sci USA 91, 85178521 (1994)