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Fibroblast-like synoviocytes (FLS) in the intimal layer adopt a pro-inflammatory phenotype under chronic stimulation, secreting cytokines such as IL-1, TNF-, IL-6, and chemokines that attract monocytes and perpetuate synovitis

Jasjit Singh

Omega-3 fatty acids: 1,000-2,000mg EPA/DHA daily

*Correspondence: Hongmei Li, [email protected] Zhang, [email protected] This article was submitted to Mitochondrial Research, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

10.3389/fnhum.2014.00537 47 HuB.SunS