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Enzymes that produce ROS, including ALOX, xanthine dehydrogenase, NADPH oxidase, and the mitochondrial electron transport chain complex, bind to iron, heme, or iron-sulfur clusters

In fact, the South African Department of Health and the WHO include folate and B12 in their standard nutritional recommendations for pregnant women

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10.1016/j.freeradbiomed.2011.03.042 Free Radic Biol Med

92 In another study on tumor metabolism, Sullivan et al