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At 1.67 mg/mL, the maintenance dose of 2.4 mg requires 144 units, which exceeds a standard 100-unit syringe

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HCN4 is a primary component of the sinoatrial node current, accounting for 70%80% of the If current, and is implicated in various cardiovascular conditions, including sinoatrial node dysfunction and arrhythmias (Schweizer et al., 2014)