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In the moment, box breathing (4 counts in, 4 hold, 4 out, 4 hold) activates the parasympathetic nervous system and reduces cortisol within minutes, providing a faster stress-relief response than most other non-pharmacological techniques

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observed that patients with sepsis show higher activity of neuraminidase, which affects erythrocyte rheology [381]

It is also useful for those looking to improve cognitive function or support cardiovascular health