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The B12 found in fortified foods and supplements is unbound, or free, and therefore is able to be absorbed even by people with absorption conditions, explains Bailey Franklyn, an Ontario-based registered dietitian

Packaging: Sealed research vial

Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation

People who have diseases that affect the intestines, such as Crohn's disease or celiac disease, are also at risk for vitamin B12 deficiency