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f , Representative bright-field micrographs of Jurkat SLC25A39 knockout cells transduced with the indicated sgRNA at the end of the cell proliferation assay

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For the spheroid 3D invasion assay, U373 and U87 cells were seeded into round-bottom 96-well plates and cultured for 2 days to allow spheroid formation

These findings are significant as they illustrate that hydrolyzed collagen, which is more readily absorbed by the body, can significantly replenish depleted collagen levels, improving many aspects of health, from skin appearance to joint and muscle function