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The compounds quinolinium scaffold confers membrane permeability that enables intracellular enzyme inhibition, distinguishing it from earlier polar NNMT inhibitor scaffolds that did not effectively enter intact cells

KPV (Lys-Pro-Val) is an u03b1-MSH-derived tripeptide investigated for NF-u03baB inhibition and anti-inflammatory cytokine modulation, adding an inflammatory signaling dimension

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