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GIP also appears to have direct effects on adipose tissue, potentially improving the way fat cells respond to metabolic signals

Oral therapy is generally unsuitable for pernicious anaemia or conditions affecting the terminal ileum (where B12 is absorbed), as these patients lack intrinsic factor or have damaged absorption sites

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The treatment, in this case, usually follows by means of having daily injections for a week or so, then injections every few days for a month, after which maintenance doses are usually given every one to two months for life