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10.1089/ars.2022.0067 33 HauensteinS.ZhangC.-M.HouY.-M.PeronaJ
R.FosterA
5.1.2 Enhancement of gut and bloodbrain barrier integrity Recent studies have shown that a vicious cycle of inflammation and oxidative stress is created at the renal level by the influx of uremic toxins and urea into the gastrointestinal lumen via the enterohepatic cycle, which exerts a selective pressure that encourages the excessive growth of bacterial species that produce urease, uricase, indole, and p-cresol-forming enzymes with a reduction in SCFAs-producing species (Vaziri et al., 2013
nevertheless, these have not been characterised in relation to bone health
These free radicals, generated as byproducts of normal metabolic processes or introduced through external factors like pollution and UV radiation, can damage cells and contribute to various akin and health issues
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