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This lack of efficacy may be attributed to the low plasma and sputum concentrations of NTZ and the high plasma protein binding of tizoxanide, the active metabolite of NTZ [80], highlighting the need for further pharmacokinetic optimization and clinical research to better understand its potential role in TB treatment

As a solution, I favor making approved research chemicals their own category of consumer product separate from approved drugs and dietary supplements

Angelidi, A

Anti-inflammatory pathways of -MSH peptides.Endocrine Reviews(2010)

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