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Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, et al

Moreover, a novel mouse model engineered to have enhanced cholesterol synthesis by SREBP-2 overexpression superimposed to APP/PS1 mutations triggered A accumulation and tau pathology ( in vivo replenishment of mGSH with cell- permeable GSH monoethyl ester (GSHEE) attenuated neuropathological features of AD in SREBP-2/APP/PS1 mice

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