PARP inhibitors , including olaparib and niraparib , impair DNA repair in BRCA-mutated cells and are approved for ovarian, breast, pancreatic, and prostate cancers
Interspecies variability in gut microbiota responses: rodent gut microbiota is dominated by Firmicutes and Bacteroidetes at ratios differing markedly from human populations, and lacks key human-enriched genera such as Prevotella and Blautia
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Shin J, Park H, Kim H, et al