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Toll-like receptors: significance, ligands, signaling pathways, and functions in mammals
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Physiologically, endoplasmic reticulum is responsible for several cellular functions including protein biosynthesis, folding, and transport, calcium storage and gated release, and lipid biosynthesis [45]
Functional studies have further demonstrated that MFAP2 knockdown suppresses tumor growth and is positively correlated with regulatory T cells (Tregs) and immune checkpoints such as CTLA4 and TIGIT, highlighting its potential as a prognostic biomarker and therapeutic target
