For example, individuals homozygous for the common MTHFR C677T polymorphism have a reduced activity of MTHFR enzyme, impaired folate metabolism and high homocysteine concentrations and may have higher requirements for folate and riboflavin (Reference McNulty, Dowey and Strain14)
72 highlighted the fact that senescent cancer cells could be used as cancer vaccine by activating the antitumor immunity
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Owing to its unique structure and mode of action, SS-31 demonstrates potential therapeutic value across cardiovascular diseases, neurodegenerative disorders, kidney injury, and myopathies associated with mitochondrial dysfunction 1-6
MO also exhibits antitumor properties, including cytotoxic, antiproliferative, chemoprotective, and anti-inflammatory activities in diverse types of tumors (Guevara et al., 1999