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Advanced picocell delivery improves penetration and effectiveness

A subcutaneous injection is designed to deliver medication into the layer of fatty tissue located just beneath the skin

Tissue structure controls how inflammation signals spread and resolve

Here, we determine structures of cagrilintide bound to Gs-coupled, active, amylin receptors (AMY 1 R, AMY 2 R, AMY 3 R) and calcitonin receptor (CTR) and compare cagrilintide interactions and the dynamics of receptor complexes with previously reported structures of receptors bound to rat amylin, salmon calcitonin or recently developed amylin-based peptides

Yu W, He J, Cai X, Yu Z, Zou Z, Fan D