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Freedman ND, Silverman DT, Hollenbeck AR, Schatzkin A, Abnet C

Surgeon General of the United States (1964)

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This agent, which was originally marketed as an antidepressant, is hypothesized to promote smoking cessation by inhibiting the reuptake of dopamine and norepinephrine in the central nervous system 54 and may function as a nicotinic acetylcholine-receptor antagonist