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In human studies, statistical differences between Control and HyperSperm groups were analyzed using Wilcoxon matched-pairs signed rank test for safety analysis, Fishers exact test for fertilization and embryo development, or a log-rank test (Mantel-Cox) for developmental times

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When the various blood vessel compartments were considered, venous cord blood exhibited higher concentrations of total glutathione-precursors, total sulfur AAs (as well as for arterial cord blood), compared with maternal blood, particularly in moderate IPTB cases, regardless of treatment (see statistical significancies in Supplemental Table S5)