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& Kuhlman, B

While glia-derived glutamine provides 50-60% of glutamate neurotransmitter, when the pathway is blocked with MeAIB excitatory transmission abruptly decreases but rapidly recovers, consistent with endogenous neuronal sources of glutamate neurotransmitter (15)

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Behav Brain Res (2015) 287:5972

Eukaryotic COG0523 Proteins Landmark studies published in 2022 establish that a eukaryotic COG0523 protein, named ZNG1 for Zn-regulated GTPase metalloprotein activator 1, fulfills all the criteria that one would anticipate of a metallochaperone for methionine aminopeptidase-1 (METAP1) in vertebrates and the yeast Saccharomyces cerevisiae , a finding recapitulated recently in plants