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Increased intracellular FFAs activate a range of gene families involved in the functional regulation of the endoplasmic reticulum, crucial for LD formation and lipid storage dynamics [97]

doi:10.1080/09513590.2018.1499086

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Caspase-11, activated by LPS, can cleave Gasdermin D into polypeptides and form nanopores in the cell membrane, causing pyroptosis and the release of the cytokine IL-1 (103, 104)

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