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This RyR2 dysregulation causes diastolic SR Ca 2+ -leak, thereby increasing the incidence of potentially proarrhythmic spontaneous SR Ca 2+ -release events (SCaEs), which initiate transmembrane Ca 2+ -extrusion through the electrogenic NCX, producing depolarizing transient inward currents

I always forget if I put that in or took it out, but yes, I woke up to a giraffe

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