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Rodrigues C, Milkovic L, Bujak IT, Tomljanovic M, Soveral G, Cipak Gasparovic A

This is achieved by alleviating the inhibition of carnitine palmitoyltransferase 1 (CPT1), which is mediated by the local production of malonyl-CoA at the outer membrane of the mitochondria, via ACC2

The peptide's targeted mechanism of action and rapid clearance contribute to its favorable tolerability profile

10.1016/j.jaci.2009.12.980 37 ChaungH