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Adjustment for misclassification would be difficult, as denial rates are likely to vary by aspects of the study design, the way questions are asked, and also by sex, age, location and other demographic variables

LTDL, Legacy Tobacco Documents Library

Experts have calculated that millions of lives could be saved if all smokers switched to e-cigarettes because they do not contain harmful tar

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One study using positron emission tomography found that nicotine administration altered brain activation patterns in smokers and ex-smokers