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Its mechanism is strictly enzymatic (NNMT inhibition)

This central action provides a strong basis for its role in neuroprotection against biochemical insults and stress

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Symptoms of severe vitamin B12 deficiency can include visual disturbances, severe joint pain, paresthesia (tingling in the hands and feet), memory problems, depression, anxiety, poor muscle function, ataxia (impaired balance and coordination), changes in reflexes and even infertility