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Furthermore, upregulation of voltage-gated Ca 2+ channels (VGCCs), particularly CaV1.3, promotes resistance to androgen deprivation therapy (ADT) and the progression of castration-resistant prostate cancer (CRPC) [32]

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Reconstitution Best Practices Add bacteriostatic water slowly along the inner vial wall of the lyophilized peptide vial never inject directly onto the lyophilized powder cake, as this can cause local denaturation

Hudson and Snyder, 2006)