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HO-1, an intracellular enzyme implicated in anti-ferroptotic mechanisms, ameliorates fibrosis by inhibiting the expansion and stimulation of HSCs upon induction with magnesium isoglycyrrhizinate [227] (Fig
1 Introduction The glutathione peroxidase family (GPX) is a family of antioxidant enzymes that are an essential class of selenoenzymes in mammals ( 2 O 2 or organic hydroperoxides to water or corresponding alcohols, thereby mitigating their toxicity ( In mammals, GPX works with superoxide dismutase and catalase to form an enzymatic antioxidant system that reduces reactive oxygen species (ROS) and limits their toxicity
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Hyaluronan: a modulator of the tumor microenvironment