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The dose-response curve in animal studies shows activity across a wide range, but there is a floor below which effects diminish (Krivic et al., 2006)

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Meibomian gland probing (MGP) effectively treats obstructive Meibomian gland dysfunction (OMGD) by mechanically clearing the obstruction or blockage of each glands lumen or pathway, or by releasing the periductal cinching around the gland thus restoring the integrity and patency of the glands central ducts

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