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In vitro studies demonstrated that amentoflavone inhibits proliferation and induces apoptosis in cytokine-stimulated HaCaT keratinocyte cells by downregulating cyclin D1, interleukin-17A (IL-17A), and IL-22

The N-terminal periplasmic domains also interact with the components of the cytoplasmic membrane-embedded platform of the secretion machinery, to promote channel opening, cargo docking, and subsequent release 26,27

Verghese RJ, Mathew SK, David A

- Spray the product on acne and dark skin areas