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On the other hand, angiogenesis in the CNS is also essential for processes such as embryonic development, recovery from ischemic stroke-type incidents, and recovery from traumatic brain injury (Vallon and Chang 2014)

Some other critical roles assigned to glutathione in the body include: Neutralization of superoxide radicals Cofactor for several antioxidant enzymes Regeneration of vitamins C and E Neutralization of free radicals produced by liver metabolism of chemical toxins Transportation of mercury out of cells and the brain Regulation of cellular proliferation Vital to mitochondrial function and maintenance of mitochondrial DNA (mtDNA) Glutathione has been shown to be very important in helping prevent hyperpigmentation, helping to prevent melanogenesis, the generation of melanin in the skin

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ROS-mediated formation of disulfide bonds averts the linkage of TCP to the CYC promotors [136]

Schapkaitz, I