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Olesoxime Olesoxime is an experimental compound believed to stabilize mitochondrial permeability transition pores (Bordet et al., In vitro studies showed increased motor neuron survival in a motor neuron degeneration model in rats (Bordet et al., G93A transgenic mice with olesoxime improved motor function in the hanging grid test, delayed the onset of body weight loss and prolonged survival by 10% (Bordet et al., 2012)

[DOI] [PubMed] [Google Scholar] 24.Ferraris C, Cooklis M, Polakowska RR, et al

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