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In addition to the inherent challenges associated with these agents, Gln metabolism lacks tumor specificity and involves multiple metabolic pathways within cells, which can lead to false positives in areas of high metabolic activity

Negrao MV , Molkentine D, Paula AG, Hover L, Nilsson M, Vokes N, Engstrom L, Calinisan A, Waters L, Briere DM, Hallin J, Blumenschein GR, Skoulidis F, Kopetz SE , Hong DS, Gibbons DL, Olson P, Christensen J, Heymach JV