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Any decision to combine these compounds should involve a healthcare provider who understands both mechanisms and can monitor for unexpected interactions

While supplementing with large doses of B12 will reduce MMA levels more than will smaller doses, there are no clear benefits (more info in Appendix A

The gap between published animal data and practical human protocols will narrow as pharmacokinetic studies expand, but until then, the most reliable 5-amino-1mq dosage protocol starts with flawless preparation

Susulic VS, Frederich RC, Lawitts J, Tozzo E, Kahn BB, Harper ME, Himms-Hagen J, Flier JS, Lowell BB

Mecobalamin normalizes axonal transport of skeletal protein in sciatic nerve cells