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Increasing injection volume to compensate for aggregation-related bioavailability loss is unreliable because aggregation is non-uniform some peptide remains monomeric while aggregates range from 50200 nanometres

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Adv Exp Med Biol 317:1316 Li Q, Li J, Zhang L, Wang B, Xiong L (2007) Preconditioning with hyperbaric oxygen induces tolerance against oxidative injury via increased expression of heme oxygenase-1 in primary cultured spinal cord neurons