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A search on PubMed returns many papers on rodents and cell models, and reviews on PubMed Central describe it as a possible therapy rather than a proven one

That would absolutely be too much

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Caspase-1 is the effector component of the NLRP3 inflammasome and is activated through proximity-induced autocatalytic activation upon recruitment to the NLRP3 inflammasome

(PubMed) Wilkinson TJ, Hanger HC, George PM, Sainsbury R