Macromolecule Content Total Structure Weight: 24.19 kDa Atom Count: 1,657 Modeled Residue Count: 185 Deposited Residue Count: 208 Unique protein chains: 1 Experimental Data Method: X-RAY DIFFRACTION Resolution: 2.10 R-Value Free: 0.205 (Depositor), 0.208 (DCC) R-Value Work: 0.156 (Depositor), 0.165 (DCC) R-Value Observed: 0.158 (Depositor) Unit Cell : Software Package: Deposition Data Released Date: 2006-07-25 Deposition Author(s): Johansson, C., Kavanagh, K.L., Rojkova, A., Gileadi, O., von Delft, F., Arrowsmith, C., Weigelt, J., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC) Revision History (Full details and data files) Version 1.0: 2006-07-25 Type: Initial release Version 1.1: 2008-05-01 Changes: Version format compliance Version 1.2: 2011-07-13 Changes: Advisory, Derived calculations, Version format compliance Version 1.3: 2018-01-31 Changes: Structure summary Version 1.4: 2021-10-20 Changes: Database references, Derived calculations Version 1.5: 2023-08-30 Changes: Data collection, Refinement description

MaMa et al., Particularly pertinent is the demonstration that HGF is a potent neurotrophic factor for many neuronal cell types (Kato et al, 2009) including motoneurons (Eisen et al., 2009
As natural hormones, the GLP-1 and amylin are short-lived
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It is approved in more than 45 countries, including Austria, Germany, Russia, China, and South Korea for conditions including stroke, traumatic brain injury, and dementia