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To maintain redox balance, cancer cells must synthesize glutathione from glutamate, glycine, and cysteine (237)

In the kainate and pilocarpine rat experimental models of TLE, ROS production through NOX activity is associated with microglial activation and is responsible for neurodegeneration in these models (Patel et al., 2005

Erastin induces considerable apoptosis and reduces the growth capacity of metastatic colorectal cancer, with IC50 values 3-fold lower compared with those of sulfasalazine (SASP), which suggested that erastin is more effective compared with SASP (54)

It also serves as a cofactor for enzymes involved in DNA maintenance, cellular stress responses and metabolic balance

The safety and effectiveness of amoxicillin for the treatment of upper respiratory tract infections, and infections of the genitourinary tract, skin and skin structure and lower respiratory tract have been established in pediatric patients