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Picrotoxin acts as a competitive antagonist of GABAARs, acting on synapses as a non-competitive channel blocker for GABAARs chloride channels, specifically the GABA-activated chloride ionophore [229]

This multi-target approach may explain why BPC-157 seems effective for conditions that resist single-mechanism treatments

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It also participates in the metabolism of fatty acids and amino acids in the hair follicle