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No amplification was detected for one mRNA, PAPLN

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[48] Some people use e-cigarettes while continuing to smoke conventional cigarettes(dual use), for example during quit attempts or in situations where smoking is restricted

In contrast, lower-SES people who smoke are more likely to engage in dual use, continuing to smoke while also using e-cigarettes, potentially due to limited access to cessation support, greater nicotine dependence, or uncertainty about the health benefits of switching [32, 40]