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doi: 10.1016/j.biopha.2023.114878

Pairing a local repair signal with a systemic one is the rationale behind the combination

Evidence strength: Moderate based on animal retinal injury models showing significant protection

Chang, C.-H., Tsai, W.-C., Lin, M.-S., Hsu, Y.-H., & Pang, J.-H

In physiological conditions, selenoproteins are an effective defense system against a large amount of ROS, which thyrocytes constantly generate on their surface in order to accept electrons from oxidative reactions ( 2 O 2 is a necessary substrate for TPO