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The demonstration that OEA is the most active endogenous ligand for GPR119 is of particular interest since previous work has demonstrated that OEA, when administered to laboratory animals, causes a significant reduction in food intake and body weight gain

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Although statins markedly reduce cardiovascular events in both primary and secondary prevention, many patients still experience recurrent adverse events

For peptide nucleic acids (PNAs), the sugar-phosphate backbone is replaced by a peptide backbone, which retains the specific binding ability with DNA/RNA and offers higher affinity and better stability than natural nucleic acids