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Elevated levels of oxidative stress can impair endothelial function, promote inflammation, and contribute to plaque formation in arteries

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Frequency Considerations and Site Rotation Injection frequency impacts both therapeutic outcomes and practical administration considerations

These effects were more noticeable in longer trials and when ALA was combined with dietary changes.29 A 2020 dose-response meta-analysis confirmed small but statistically significant reductions in weight and BMI across 18+ randomized controlled trials.30 However, waist circumference (WC) a marker of central obesity showed no consistent change, and the benefit appeared greater in women and with longer treatment durations