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No serious side effects

No controlled trials have been performed, but antibiotic therapy is used widely for this treatment indication and is considered to be the first-line therapy in combination with immunosuppressive or biological therapies

It is an intriguing source of bioactive components, including cynaropicrin, phenolics, minerals, inulin, fiber, and sesquiterpene lactones, making it a functional food with great nutritional value

3 This makes it the most common site for sun-driven pigmentation, and the reason why actinic damage concentrates there almost exclusively in outdoor workers and chronic sun exposers