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A 500 mcg dose of a 99% pure product provides a known variable, whereas a lower purity product introduces unknown substances and an inaccurate amount of the active peptide
Neurobrucellosis: the great mimicker
Additional oral supplementation with polypodium leucotomos extract (PLE) at 480 mg twice daily can be helpful (anecdotal evidence, unpublished)
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However, not all individuals produce UroA efficiently owing to variations in gut microbiome composition, which has led to the development of direct supplementation strategies to achieve consistent levels across different populations (Reference Singh, DAmico and Andreux11)
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