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To put that in perspective, a 10 mg/kg dose in a 250-g rat, scaled allometrically to a 70-kg human using the FDA's body surface area conversion factor of 6.2, translates to roughly 1.6 mg/kg, or 112 mg for a 70-kg person 7

KPV is the tripeptide Lys-Pro-Val , the C-terminal fragment of -MSH , investigated in cell and animal models as an anti-inflammatory agent acting on inflammatory signalling

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