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Tumor metabolic reprogramming has emerged as a hallmark of cancer, and among various metabolic pathways, lysophosphatidic acid (LPA)a bioactive lipid mediatorhas been increasingly implicated in PCa progression, particularly CRPC transformation

MathewARDi MatteoGLa RosaPBarbatiSAManninaLMorenoSet al

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For immunohistochemical staining, the tissue sections were inactivated by endogenous peroxidase with 3% hydrogen peroxide for 10 min and blocked with goat serum for 30 min

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