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When assessing non-essential amino acid profiles, we found that on average, the vast majority fell within healthy reference ranges for adolescents (Supplementary Fig

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As mentioned previously, mast cells and keratinocytes can induce vascularization through the increment in VEGF secretion, enhanced TGF- and FGF-2, thus can create more, larger, and highly dilated vessels which are considered important targets in melasma treatment (Kim et al., 2005

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