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Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome

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High-dose metformin plus temozolomide shows increased anti-tumor effects in glioblastoma in vitro and in vivo compared with monotherapy

A: For chronic in vivo studies, daily administration of a specific 5-Amino-1MQ dosage is common to maintain consistent systemic exposure