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Conversely, high protein levels of IGF1 and its receptors, accompanied by a reduction in AKT/mTOR signaling pathways resulting from resistance exercise training, are associated with increased autophagy activity in aged skeletal muscles ( IGF1 expression is significantly reduced in ATG7 knockout mice, indicating that IGF1 plays a beneficial role in regulating autophagy (Zecchini et al., 2019)

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Seven of the main active ingredients of XYS are thought to be related to its antidepressant effects: abrin, aloin, emodin, glycomycin C, kaempferol, luteolin, paeoniflorin, and quercetin

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74 The antioxidant function of serum uric acid reflects the multifaceted and complex nature of its physiological role