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The study identified increased proportions of pro-inflammatory and mesenchymal fibroblast subpopulations, elevated p16 protein and SA--galactosidase-positive cells, and enhanced SASP gene expression in keloid tissue

found that inhibiting Gln uptake increases the sensitivity of ovarian cancer cells to paclitaxel by blocking the activation of the mTORC1/S6K signaling pathway, downregulating Mcl-1 levels, and increasing Bcl-2 phosphorylation (96)

These factors may independently or interactively contribute to ME/CFS

In early rodent work, BPC 157 showed protective effects on the gut lining and accelerated healing of ulcers